The Knowledge Hub

A central resource for breast imaging insights, practical guidance, industry references, and operational support: articles that span all programs and disciplines.

8 articles
The Knowledge HubIn-Depth

MQSA: The Unlikely Birth of the Only Imaging Modality with Real Federal Teeth

In 1992, the Mammography Quality Standards Act became the only federal law mandating quality oversight for a single diagnostic imaging modality. This is how Betty Ford's candor, failed voluntary accreditation, and congressional urgency combined to create the regulatory framework that still governs every mammography facility in the country.

Aug 22, 20265 min read
The Knowledge HubStandard Read

What Is Breast Density?

Breast density describes the relative proportion of fibroglandular to fatty tissue visible on a mammogram. It simultaneously lowers mammographic sensitivity through a masking effect and functions as an independent risk factor for breast cancer. As of September 10, 2024, the MQSA Final Rule requires every facility to report density using a standardized four-category lexicon and include prescribed notification language in every patient lay letter.

Aug 20, 20265 min read
The Knowledge HubIn-Depth

What Is “Lost to Follow-Up” in Mammography?

Lost to follow-up (LTFU) is the operational state in which a patient with an unresolved positive mammogram assessment can no longer be reached after documented outreach has been exhausted. This article defines LTFU, distinguishes it from the earlier overdue state, quantifies its audit impact under MQSA, and outlines the closed-loop tracking architecture required to minimize its occurrence.

Aug 19, 20267 min read
The Knowledge HubIn-Depth

What Is DCIS (Ductal Carcinoma In Situ)?

Ductal carcinoma in situ (DCIS) is a stage 0, noninvasive proliferation of abnormal cells confined within breast ducts. It is both a clinical entity with a non-obligate progression pathway to invasive cancer and a high-stakes audit outcome under MQSA. This article covers definition, epidemiology, diagnosis, treatment, and the operational closed-loop tracking requirements every facility must meet.

Aug 19, 20269 min read
The Knowledge HubIn-Depth

What Is PPV in Mammography? PPV1, PPV2, and PPV3 Explained

PPV in mammography is measured at three distinct clinical stopping points. Learn how PPV1, PPV2, and PPV3 expose different operational failures in the breast imaging audit pathway under FDA-MQSA and ACR BI-RADS requirements.

Aug 18, 20269 min read
The Knowledge HubIn-Depth

Downstream Revenue Estimator: Methods and Validation Note

A complete, reproducible documentation of the Downstream Revenue Estimator's arithmetic: the three-tier revenue formulas, two-population detection logic, treatment blending, largest-remainder display rounding, a worked year-1 example, and the full 420-configuration validation matrix.

Aug 17, 20268 min read

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